With your support we can CURE CJD
A few final steps remain to turn hope into reality and stop this dreadful disease
A few final steps remain to turn hope into reality and stop this dreadful disease.
Support the scientific breakthrough and help us fund PRN100 clinical trial phase II.
Together we can make an impact in the fight against this disease
The Cure CJD Campaign
The Cure CJD Campaign was set up by a group of individuals personally affected by CJD and prion diseases.
The vision of the Campaign is to raise funds to support the work of the MRC Prion Unit at University College London (UCL) and to help fund the £10 million needed to take PRN100 (a potential treatment) through clinical trial phase II.
The Cure CJD Campaign was set up by a group of individuals personally affected by the disease.
The vision of the Campaign is to raise funds to support the work of the Medical Research Council (MRC) Prion Unit at University College London (UCL) to develop a treatment or cure for CJD, and to raise awareness and understanding of this disease.
With your support, we will be closer to finding a treatment for CJD.
Finding a treatment for CJD and prion diseases
CJD is currently responsible for 1 in 5000 deaths in the UK each year. Most patients die within just one year after the onset of symptoms, some within weeks of diagnosis, and others degenerate over several years.
There is currently no treatment or cure for CJD, but world-leading research at the MRC Prion Unit at UCL developed an experimental antibody treatment called PRN100. This was designed to stop prion proteins from malfunctioning in the brain.
CJD is currently responsible for 1 in 5000 deaths in the UK each year. Sadly, the disease usually leads to death within one year of onset of illness, and often much sooner.
There is currently no treatment or cure for CJD, but every day scientists and doctors are getting closer to finding a treatment. In fact, progress has already been made, but we still have a long way to go.
“We are filled with hope to see such a promising treatment within reach – one that could halt these terrifying and fatal diseases and contribute to the broader fight against Alzheimer’s and other neurodegenerative conditions.”
families will not have
to face a loss like ours.”
Charlotte Saigne, Chair of Cure CJD Campaign, with her brother Frédéric who died of genetic prion disease in 2020
died as a result of Acquired CJD.
“We are filled with hope to see such a promising treatment within reach – one that could halt these terrifying and fatal diseases and contribute to the broader fight against Alzheimer’s and other neurodegenerative conditions.”
A small number of patients were given PRN100 in an experimental treatment programme in 2018/2019 and PRN100 showed remarkably positive early-stage test results in humans.
After 20 years of dedicated research, £10 million is needed to take PRN100 through clinical trial phase II, a fraction of the cost of comparable research
World-leading research at the MRC Prion Unit at UCL developed an experimental antibody treatment called PRN100. This was designed to stop prion proteins from malfunctioning in the brain. Positive results were shown in laboratory testing and a small number of patients were given PRN100 in an experimental treatment programme in 2018/2019.
However, more vital research is needed to advance PRN100, and it will cost many millions to conduct a full clinical trial. With your help, we can reach that target and find a cure for CJD.
The Cure CJD Parliamentary Reception
Please register your interest for Cure CJD’s parliamentary reception
We have raised £1 million so far
Thanks to our generous supporters, this is a great start, but much more is needed to continue vital research and help to make a viable treatment. With your help, we can reach our target.
With your support there is hope
Together we can make an impact in the fight against this disease
We've reached £1 million in donations!
In September 2024 the Cure CJD Campaign reached £1,000,000 in donations since it started in 2016. This is a significant achievement and testament to everyone who has sadly been touched by this dreadful disease.
Since the campaign started, we have been able to fund researchers at the MRC Prion Unit at UCL, contribute to the delivery of the first experimental treatment programme of PRN100 and significantly raise the profile of CJD.
We would like to thank every single person who has contributed to the campaign. We will continue to support the Prion Unit in their world-leading work and raise as much as possible to help fund PRN100 clinical trial phase II.
In September 2024 the Cure CJD Campaign reached £1,000,000 in donations since it started in 2016. This is a significant achievement and testament to everyone who has sadly been touched by this dreadful disease. Since the campaign started we have been able to fund researchers at the MRC Prion Unit at UCL, contribute to the delivery of the first experimental treatment programme of PRN100 and significantly raise the profile of CJD. We would like to thank every single person who has contributed to the campaign. We will continue to support the Prion Unit in their world-leading work and raise as much as possible to help fund a clinical trial.